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Members' feedback

"I'm finding it shocking and surprising the number of new people joining the community. Let me explain. I was diagnosed with AVN first in both knees back in 2005, over the next few years it was found in both hips and shoulders. I had never come across AVN before and felt like I was the only person with it, I was always having to explain to people what it was."
 
"Thankfully I found this website and community over a year ago and realised I was not the only one suffering with AVN, it has been such a help talking to fellow sufferers who understand what I am going through."
 
Text taken from a recent post in our community forum.

Join us

If you are suffering from avascular necrosis AVN Osteonecrosis ON, or are close to someone that is, please consider joining our AVN Charity UK community. You will find many shared experiences about AVN and how it affects each of us differently, importantly there are also excellent success stories about the road to "Pain Free".
 
We also welcome any health professionals who are involved in any way with Avascular Necrosis AVN, please let us know how you think you can help.

AVN due to cancer treatmentMRI scan image, clearly displaying an unusual case of avascular necrosis AVN in the long bones, caused by cancer treatment.MRI scan image, clearly displaying an unusual case of avascular necrosis AVN in the long bones, caused by cancer treatment.

Avascular Necrosis can be a side effect of treatment for several different types of cancer.

The main risk factors for developing AVN as a result of cancer treatment include treatment with:

  • Corticosteroids such as dexamethasone or prednisolone (these remain leading cause of AVN)
  • Bisphosphonates
  • Certain types of chemotherapy
  • Radiotherapy to weight-bearing joints and Total Body Radiation
  • Bone Marrow or Stem Cell Transplantation
  • Patients who are being treated for acute myeloid leukaemia, acute lymphoblastic leukaemia, lymphomas, testicular cancer, ovarian cancer, breast cancer, and multiple myeloma have an increased risk of developing AVN regardless of the treatment they receive
  • Being older than 10 years old whilst receiving treatment

The period of time from treatment to onset of AVN can vary greatly. Although it is usually diagnosed whilst undergoing cancer treatment, it can rarely be diagnosed years later when symptoms become apparent.

It is important to remember that although AVN can be an unwanted side effect of cancer treatment, it is very important not to discontinue any medication or reduce the dosage without the instruction of your medical team as the medicines that can cause AVN are also very effective at treating cancer.

Last Updated on Thursday, 01 January 2015 21:18